What is priapism: 

Priapism is an involuntary erection which lasts more than 4 hours and is unrelieved by ejaculation. This condition is a true urological emergency and early treatment allows the best chance for functional recovery.

How to prevent priapism when taking Tri-Mix or other penile injection therapies (ICP):

  • NEVER take Tri-Mix or any ICP injection within same 24hr period as Viagra/Cialis/Levitra or other ED meds.
  • Start LOW and go SLOW with your dose. Never start higher than 0.05-0.12ml (5-12 units on syringe) for the FIRST injection. Then gradually increase from there for optimal results.

If priapism occurs:

  • Apply ice to perineum/scrotal area- You can use a frozen bag of fruit or vegetables if an ice pack is not available.
  • Walk/jog upstairs- This can help redirect blood flow from the penis.

Over-the counter medications to take:

  • Sudafed– take 60mg-150mg orally
  • Benadryl– take 25mg-50mg orally
  • Amyl Nitrate:“Poppers” is another name Amyl Nitrate and is sold in “head shops” or “smoke shops” as an “air freshener”. It is also available online. Many guys who are very experienced with ICP injections use Amyl Nitrate to treat priapism when it occurs. It is very safe if used properly. The possible side effects include headaches, decreased blood pressure and potential loss of arousal after a few minutes.

How to use amyl nitrate to treat priapism: Usually sold as “poppers”, amyl nitrate usually comes in a bottle containing breakable capsules. You do not take amyl nitrate orally, instead break the capsule and inhale (sniff) the broken capsule. Inhale over 15-30 seconds or for 2-6 nasal inhalations to help reverse erection.

Prescription medications

Terbutaline– 10mg once, then take another 5mg-10mg 15 minutes after the first dose only if needed. If you have been prescribed Tri-Mix or any other ICP injection and are concerned about priapism you may request a prescription for Terbutaline to have on hand.

If these do not work and erection has been present for 4hrs and/or is exquisitely painful then immediately visit the ER for treatment.

Instructions for Intramuscular Injections

Intramuscular Injection

Instructions for Subcutaneous Injections

Subcutaneous Injection

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