Optimizing Your Health: The Latest Medical News & Opinion from Dr. Rand McClain

I know your email box and Facebook pages are filled with information about “Coronavirus” aka COVID-19 aka SARS-CoV-2 (who knew so many of your Facebook friends were scientific experts in the field of viral pathology and epidemiology!). 

In an effort to help you separate fact from fiction, I offer you some links to websites of trusted sources of information:

From these sites you can gather that there may be promise for many patients for both treatment and prophylaxis using some drugs already available such as remdesivir (now temporarily withdrawn from the market indefinitely by its sole maker, Gilead), hydroxychloroquine (or chloroquine), and hydroxychloroquine with azithromycin, and, perhaps even lopinavir and ritonavir (though early results were negative, the study size using lopinavir and ritonavir was too small to draw definitive conclusions, yet). Scientists are currently investigating other extant drugs including valproic acid, haloperidol, indomethacin, metformin, ribavirin, rapamycin, captopril, lisinopril, S-verapamil, chloramphenicol, tigecycline, and linezolid.
 

There are also anecdotal reports from China (http://chinaxiv.org/abs/202002.00084) (http://chinaxiv.org/abs/202002.00080) and ongoing current clinical trials (https://clinicaltrials.gov/ct2/show/NCT04252118) using human mesenchymal stem cells to treat coronavirus infection and blunt the overactive immune response and subsequent damage to the lungs resulting in pneumonia which is the source of most deaths or permanent morbidity secondary to lung scarring. There are also completed and currently ongoing clinical trials showing benefits of using human mesenchymal stem cells for multiple causes of lung injury.

So, what do we do?

First of all, economics aside and strictly focusing on the medical aspects, the expert advice is on point, and, to be prudent we should:

  • Wash hands frequently and properly
  • Keep hands away from face, eyes and mouth
  • Remain "socially distanced" as much as possible by staying home and otherwise maintaining a 6-foot distance from others
  • Eat nutritiously
  • Get adequate sleep (7-9 hours nightly) and try to get to bed and rise at a consistent hour
  • Stay hydrated
  • Engage in light to moderate exercise at least 3 times per week
  • Do your best to reduce or alleviate stress

Meanwhile, at Regenerative and Sports Medicine, we have made arrangements with our compounding pharmacies to, in the next 1 – 2 weeks, acquire and provide us with hydroxychloroquine and azithromycin (remdesivir is not only very difficult to obtain but must be delivered intravenously), both of which are relatively cheap drugs.

Anyone interested in obtaining human mesenchymal stem cells can do so by simply contacting us. We can either store them in our -80 degree F freezer at our office for local patients or we can have them remain stored in San Diego for delivery within 24 hours to anywhere in the United States. 

Note that these aforementioned treatments show promise in treating and preventing coronavirus infection, but each is considered an “off-label” treatment in the eyes of the FDA. That said, aside from a risk QT prolongation, (an electrical disturbance of the heart), which is relatively rare and associated with hydroxychloroquine and azithromycin, no serious side effects have been reported with these drugs or human mesenchymal stem cells.

Best in health,
Dr. Rand McClain

Dr. Rand McClain
 
Contact Regenerative & Sports Medicine at 310-452-3206

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